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Abstract We present results from the Chandra X-ray Observatory Large Project (878 ks in 28 observations) of the Large Magellanic Cloud supernova remnant N132D. We measure the expansion of the forward shock in the bright southern rim to be $0\stackrel{″}{.}10\pm 0\stackrel{″}{.}02$over the ∼14.5 yr baseline, which corresponds to a velocity of 1620 ± 400 km s⁻¹after accounting for several instrumental effects. We measure an expansion of $0\stackrel{″}{.}23\pm 0\stackrel{″}{.}02$and a shock velocity of 3840 ± 260 km s⁻¹for two features in an apparent blowout region in the northeast. The emission-measure-weighted average temperature inferred from X-ray spectral fits to regions in the southern rim is 0.95 ± 0.17 keV, consistent with the electron temperature implied by the shock velocity after accounting for Coulomb equilibration and adiabatic expansion. In contrast, the emission-measure-weighted average temperature for the northeast region is 0.77 ± 0.04 keV, which is significantly lower than the value inferred from the shock velocity. We fit 1D evolutionary models for the shock in the southern rim and northeast region, using the measured radius and propagation velocity into constant density and power-law profile circumstellar media. We find good agreement with the age of ∼2500 yr derived from optical expansion measurements for explosion energies of 1.5–3.0 × 10⁵¹erg, ejecta masses of 2–6M_⊙, and ambient medium densities of ∼0.33–0.66 amu cm⁻³in the south and ∼0.01–0.02 amu cm⁻³in the northeast assuming a constant density medium. These results are consistent with previous studies that suggested the progenitor of N132D was an energetic supernova that exploded into a preexisting cavity. 

Abstract Dust from core-collapse supernovae (CCSNe), specifically Type IIP supernovae (SNe IIP), has been suggested to be a significant source of the dust observed in high-redshift galaxies. CCSNe eject large amounts of newly formed heavy elements, which can condense into dust grains in the cooling ejecta. However, infrared (IR) observations of typical CCSNe generally measure dust masses that are too small to account for the dust production needed at high redshifts. Type IIn SNe (SNe IIn), classified by their dense circumstellar medium, are also known to exhibit strong IR emission from warm dust, but the dust origin and heating mechanism have generally remained unconstrained because of limited observational capabilities in the mid-IR (MIR). Here, we present a JWST/MIRI Medium Resolution Spectrograph spectrum of the SN IIn SN 2005ip nearly 17 yr post-explosion. The SN IIn SN 2005ip is one of the longest-lasting and most well-studied SNe observed to date. Combined with a Spitzer MIR spectrum of SN 2005ip obtained in 2008, this data set provides a rare 15 yr baseline, allowing for a unique investigation of the evolution of dust. The JWST spectrum shows the emergence of an optically thin silicate dust component (≳0.08M_⊙) that is either not present or more compact/optically thick in the earlier Spitzer spectrum. Our analysis shows that this dust is likely newly formed in the cold, dense shell (CDS), between the forward and reverse shocks, and was not preexisting at the time of the explosion. There is also a smaller mass of carbonaceous dust (≳0.005M_⊙) in the ejecta. These observations provide new insights into the role of SN dust production, particularly within the CDS, and its potential contribution to the rapid dust enrichment of the early Universe. 

Synthetic Notch (synNotch) receptors are genetically encoded, modular synthetic receptors that enable mammalian cells to detect environmental signals and respond by activating user-prescribed transcriptional programs. Although some materials have been modified to present synNotch ligands with coarse spatial control, applications in tissue engineering generally require extracellular matrix (ECM)-derived scaffolds and/or finer spatial positioning of multiple ligands. Thus, we develop here a suite of materials that activate synNotch receptors for generalizable engineering of material-to-cell signaling. We genetically and chemically fuse functional synNotch ligands to ECM proteins and ECM-derived materials. We also generate tissues with microscale precision over four distinct reporter phenotypes by culturing cells with two orthogonal synNotch programs on surfaces microcontact-printed with two synNotch ligands. Finally, we showcase applications in tissue engineering by co-transdifferentiating fibroblasts into skeletal muscle or endothelial cell precursors in user-defined micropatterns. These technologies provide avenues for spatially controlling cellular phenotypes in mammalian tissues. 

Abstract We present new JWST/MIRI Medium Resolution Spectroscopy and Keck spectra of SN 1995N obtained in 2022–2023, more than 10,000 days after the supernova (SN) explosion. These spectra are among the latest direct detections of a core-collapse SN, both through emission lines in the optical and thermal continuum from infrared (IR) dust emission. The new IR data show that dust heating from radiation produced by the ejecta interacting with circumstellar matter is still present but greatly reduced from when SN 1995N was observed by the Spitzer Space Telescope and WISE in 2009/2010 and 2018, when the dust mass was estimated to be 0.4M_⊙. New radiative-transfer modeling suggests that the dust mass and grain size may have increased between 2010 and 2023. The new data can alternatively be well fit with a dust mass of 0.4M_⊙and a much reduced heating source luminosity. The new late-time spectra show unusually strong oxygen forbidden lines, stronger than the Hαemission. This indicates that SN 1995N may have exploded as a stripped-envelope SN, which then interacted with a massive H-rich circumstellar shell, changing it from intrinsically Type Ib/c to Type IIn. The late-time spectrum results when the reverse shock begins to excite the inner H-poor, O-rich ejecta. This change in the spectrum is rarely seen but marks the start of the transition from SN to SN remnant. 

Abstract We show that four-dimensional superconformal algebras admit an infinite-dimensional derived enhancement after performing a holomorphic twist. The type of higher symmetry algebras we find is closely related to algebras studied by Faonte–Hennion–Kapranov, Hennion–Kapranov, and the second author with Gwilliam in the context of holomorphic QFT. We show that these algebras are related to the two-dimensional chiral algebras extracted from four-dimensional superconformal theories by Beem and collaborators; further deforming by a superconformal element induces the Koszul resolution of a plane in $$\mathbb {C}^2 \cong {\mathbb {R}}^4$$ $C^2\cong R^4$. The central charges at the level of chiral algebras arise from central extensions of the higher symmetry algebras.